Faulty homocysteine recycling in diabetic retinopathy

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Homocysteine and diabetic retinopathy.

OBJECTIVE Homocysteine is an emerging risk factor for cardiovascular and nondiabetic ocular vaso-occlusive diseases. However, studies of the relationship between homocysteine and diabetic retinopathy have reported inconsistent results. The purpose of this study was to evaluate the relationship between plasma total homocysteine concentration and diabetic retinopathy. RESEARCH DESIGN AND METHOD...

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Plasma Total Homocysteine Levels in Diabetic Retinopathy

We read with great interest the recently published article by Malaguarnera et al. [1].This studywas aimed at evaluating the plasma total homocysteine (tHcy) levels in diabetic patients with and without retinopathy for the progression of diabetic retinopathy. In conclusion, higher plasma levels of tHcy have been found in diabetic patients with proliferative diabetic retinopathy compared to both ...

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The Relationship among Homocysteine, Bilirubin, and Diabetic Retinopathy

BACKGROUND Diabetic retinopathy is a common microvascular complication of diabetes mellitus (DM) and the leading cause of blindness in adults. Homocysteine, a risk factor with toxic effects on vascular endothelial cells, and bilirubin, a protectant with antioxidant and anti-inflammatory properties on the vasculature, have been reported to be linked to vaso-occlusive disorders. Therefore, the au...

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Reduced Serum Homocysteine Levels in Diabetic Patients

Background and Objectives: Type 2 diabetes is the most prevalent form of diabetes mellitus and is associated with a variety of complications. Homocysteine is an important independent risk factor for atherosclerotic diseases in both diabetic and non diabetic subjects. The association between these two is still unclear. The aim of this study was to assess the serum homocysteine levels in uncompli...

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ژورنال

عنوان ژورنال: Eye and Vision

سال: 2020

ISSN: 2326-0254

DOI: 10.1186/s40662-019-0167-9